The PNarec method for detection of ancient recombinations through phylogenetic network analysis.
نویسندگان
چکیده
Recombinations are known to disrupt bifurcating tree structure of gene genealogies. Although recently occurred recombinations are easily detectable by using conventional methods, recombinations may have occurred at any time. We devised a new method for detecting ancient recombinations through phylogenetic network analysis, and detected five ancient recombinations in gibbon ABO blood group genes [Kitano et al., 2009. Mol. Phylogenet. Evol., 51, 465-471]. We present applications of this method, now named as "PNarec", to various virus sequences as well as HLA genes.
منابع مشابه
Relic of ancient recombinations in gibbon ABO blood group genes deciphered through phylogenetic network analysis.
The primate ABO blood group gene encodes a glycosyl transferase (either A or B type), and is known to have large coalescence times among the allelic lineages in human. We determined nucleotide sequences of ca. 2.2kb of this gene for 23 individuals of three gibbon species (agile gibbon, white-handed gibbon, and siamang), and observed a total of 24 haplotypes. We found relics of five ancient intr...
متن کاملPhylogenetic Detection of Recombination with a Bayesian Prior on the Distance between Trees
Genomic regions participating in recombination events may support distinct topologies, and phylogenetic analyses should incorporate this heterogeneity. Existing phylogenetic methods for recombination detection are challenged by the enormous number of possible topologies, even for a moderate number of taxa. If, however, the detection analysis is conducted independently between each putative reco...
متن کاملMolecular Detection and Phylogenetic Analysis of Equine Herpes Virus-1 in Horses with History or Clinical Signs in Four Provinces of Iran
BACKGROUND: Equine herpes virus-1 (EHV-1) is a major cause of economic loss in horse industry and is well recognized as a cause of abortion, respiratory disease, neurologic disorders and death of neonatal foals.OBJECTIVES: The aim of this study was to evaluate the frequency of EHV-1 in horses with clinical signs and/or history associated with this virus from four provinces of Iran (Golest...
متن کاملMEFUASN: A Helpful Method to Extract Features using Analyzing Social Network for Fraud Detection
Fraud detection is one of the ways to cope with damages associated with fraudulent activities that have become common due to the rapid development of the Internet and electronic business. There is a need to propose methods to detect fraud accurately and fast. To achieve to accuracy, fraud detection methods need to consider both kind of features, features based on user level and features based o...
متن کاملAnalysis and Diagnosis of Partial Discharge of Power Capacitors Using Extension Neural Network Algorithm and Synchronous Detection Based Chaos Theory
Power capacitors are important equipment of the power systems that are being operated in high voltage levels at high temperatures for long periods. As time goes on, their insulation fracture rate increases, and partial discharge is the most important cause of their fracture. Therefore, fast and accurate methods have great importance to accurately diagnosis the partial discharge. Conventional me...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Molecular phylogenetics and evolution
دوره 66 2 شماره
صفحات -
تاریخ انتشار 2013